Pyridine-2-Carboxylic Acid (Picolinic Acid)


pyridine-2-carboxylic acid; α-Picolinic acid, Pyridine-2-carboxylic acid;
picolinic acid; 2-Pyridinecarboxylic acid; 2-Picolinic acid; 2-Carboxypyridine

Technical Data

CAS Number: 98-98-6
Molecular Formula: C6H5NO2
Molecular Weight: 123.11
Beilstein Registry Number: 109595
EC Number: 202-719-7

FabriChem Specifications

AppearanceWhite to off-white crystalline powder
SolubilitySoluble in hot water, and glacial acetic acid; slightly soluble in alcohol
Assay 99.0% Min.
(w/w dried basis)
Melting Range136.0° – 139.0°C
Water 0.50% Max. (w/w)
Sulfated Ash 0.30% Max. (w/w)
Chloride200 ppm Max.
Iron100 ppm Max.
Heavy Metals10 ppm Max.
Lead5 ppm Max.
Arsenic5 ppm Max.
Cadmium2 ppm Max.
Mercury0.1 ppm Max.

Molecular Structure



Picolinic Acid is an organic compound. It is a derivative of pyridine with a carboxylic acid substituent at the 2-position. It is an isomer of nicotinic acid, which has the carboxyl side chain at the 3-position. It is a white solid that is soluble in water. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.

Picolinic Acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body.