Synonyms
Dipicolinic Acid, 2,6-Pyridinedicarboxylic Acid, DPA; DPAc; PDC
Technical Data
CAS Number: 499-83-2
Molecular Formula: C7H5NO4
Molecular Weight: 167.12
Beilstein Registry Number: 131629
EC Number: 207-894-3
FabriChem Specifications
| ITEMS | SPECIFICATIONS |
| Appearance | White or Off-White Crystalline Powder |
| Solubility | 0.25 gm in 10 ml of 95% ethanol soluble |
| Melting Point | 238.0° to 252.0° C |
| Water Content | 0.50% w/w Max. |
| Sulfated Ash | 0.10% w/w Max. |
| Heavy Metals: | |
| Chromium | 10 ppm Max. |
| Iron | 50 ppm Max. |
| Assay | 99.0% Min.
(w/w dried substance)
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| |
Molecular Structure
About
Dipicolinic Acid is a chemical compound which composes 5% to 15% of the dry weight of bacterial spores. Dipicolinic acid forms a complex with calcium ions within the endospore core. This complex binds free water molecules, causing dehydration of the spore. As a result, the heat resistance of macromolecules within the core increases. The calcium-dipicolinic acid complex also functions to protect DNA from heat denaturation by inserting itself between the nucleobases, thereby increasing the stability of DNA. It is also used to prepare transition metal complexes for ion chromatography.
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