2,6-Pyridine Dicarboxylic Acid (Dipicolinic Acid)

Synonyms

Dipicolinic Acid, 2,6-Pyridinedicarboxylic Acid, DPA; DPAc; PDC

Technical Data

CAS Number: 499-83-2
Molecular Formula: C₇H₅NO₄
Molecular Weight: 167.12
Beilstein Registry Number: 131629
EC Number: 207-894-3

FabriChem Specifications

ITEMS	SPECIFICATIONS

Appearance	White or Off-White Crystalline Powder
Solubility	0.25 gm in 10 ml of 95% ethanol soluble
Melting Point	238.0° to 252.0° C
Water Content	0.50% w/w Max.
Sulfated Ash	0.10% w/w Max.
Heavy Metals:
Chromium	10 ppm Max.
Iron	50 ppm Max.
Assay	99.0% Min. (w/w dried substance)

Molecular Structure

2.6-pyridine-dicarboxylic-acid-dipicolinic-acid-structure

About

Dipicolinic Acid is a chemical compound which composes 5% to 15% of the dry weight of bacterial spores. Dipicolinic acid forms a complex with calcium ions within the endospore core. This complex binds free water molecules, causing dehydration of the spore. As a result, the heat resistance of macromolecules within the core increases. The calcium-dipicolinic acid complex also functions to protect DNA from heat denaturation by inserting itself between the nucleobases, thereby increasing the stability of DNA. It is also used to prepare transition metal complexes for ion chromatography.

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