Progesterone USP | FabriChem

Synonyms

4-pregnene-3,20-dione

Technical Data

CAS Number: 57-83-0
Molecular Formula: C₂₁H₃₀O₂
Molecular Weight: 314.46
Beilstein Registry Number: 1915950
EC Number: 200-350-6

FabriChem Specifications

ITEMS	SPECIFICATIONS
Appearance	White or almost white crystalline powder
Solubility	Practically insoluble in water, freely soluble in ethanol, sparingly soluble in acetone and in fatty oils
Melting Range	126° – 131° C
Specific Rotation	+175° to +183°
Identification A Identification B	+175° to +183° IR: Reference to standard spectrum UV: Reference to standard spectrum
Loss on Drying	0.5% Max.
Assay	97.0% - 103.0%
Particle Size	To be reported
Residual Solvents	Meets USP <467> requirements

Molecular Structure

About

Progesterone, also known as P4, is an endogenous steroid hormone, produced by the corpus luteum. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, and plays an important role in brain function as a neurosteroid.

In cosmetic applications, when properly formulated, topical progesterone can slow certain age-related changes to skin. Most notably, it seems to positively impact skin’s elasticity. For this reason, Progesterone is used in anti-aging creams.