Ceramide is a brown extract refined from rice bran or rice germ. Ceramide contains a large amount of glycophingolipids which are effective antigens and immunogens. Glycophingolipids have been classified as cell surface antigens as binding sites for bacterial toxins and bacterial infection.
Ceramide contains a large amount of glycophingolipids which are effective antigens and immunogens. Glycophingolipids have been classified as cell surface antigens as binding sites for bacterial toxins and bacterial infection. Ceramides are contained in the skin and play important roles in maintaining the barrier function and homeostasis of the skin. Ceramides are found to be reduced in the stratum corneum (outermost layer of the skin) of atopic dermatitis, dry skin, and aged persons. Thus, a lack of Ceramide is considered to be a cause of wrinkles and dry skin.
• Skin hydration
• Repairs and restores dry and damaged skin
A study conducted on melanogenesis using cultured B16 melanoma cells in vitro showed that Ceramide is stronger than Ascorbic Acid, Arbutin, and Ellagic Acid in causing a skin whitening effect.
Several clinical trials have established that Ceramide has a moisturizing effect. Ceramide is absorbed by the digestive system and carried to the stratum corneum by blood circulates, thus improving the barrier and water-holding function of the skin. In a study conducted by Imokawa et al., it was confirmed that topical applications of Ceramides improved atopic dry skin conditions.
It was also reported that Ceramides may also increase the anti-allergy efficacy of skin, inhibit free radical attack and increase the inhibitory effect on elastase, collagenase, and tyrosinase. This demonstrates Ceramide’s efficacy in slowing skin aging and preventing the stress of skin.