Dehydroepiandrosterone

Synonyms

trans-Dehydroandrosterone, 3β-Hydroxy-5-androsten-17-one, 5-Androsten-3β-ol-17-one,
DHEA, Dehydroepiandrosterone, Dehydroisoandrosterone, Prasterone

Technical Data

CAS Number: 53-43-0
Molecular Formula: C₁₉H₂₈O₂
Molecular Weight: 288.42
EC Number: 200-175-5

FabriChem Specifications

ITEMS	SPECIFICATIONS
Appearance	White or almost white crystalline powder
Assay (HPLC)	98.5% - 102.0%
Melting Point	149° – 151°C
Specific Rotation	+12° to +15°
Loss on Drying	0.5% Max.
Sulfated Ash	0.1% Max.
Related Substances:	Any Impurity: 0.10% Max. Total Impurities: 0.50% Max.
Total Heavy Metals	10 ppm Max.
Lead	3 ppm Max.
Arsenic (As)	1 ppm Max.
Mercury	0.1 ppm Max.
Cadmium	1 ppm Max.
Bulk Density	Report Only
Tapped Density	Report Only
Particle Size	Report Only
Microbiology:
Total Plate Count	1,000 CFU/g Max.
Yeast & Mold	100 CFU/g Max.
Coliform	Negative
E. Coli	Negative

Molecular Structure

dehydroandrosterone-structure

About

Dehydroandrosterone (DHEA) is a negative modulator of GABAA receptors. It is a steroid secreted by the adrenal gland with both estrogenic and androgenic properties. DHEAs conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.