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Glycocholic Acid

Synonyms


glycitin;glycocholic;cholylglycine;n-cholyglycine;n-cholylglycine;cholylglycinate;glycocholic acid;clycocholic acid;n-choloylglycine;glycocholic-d4 acid

Technical Data

CAS Number: 475-31-0
Molecular Weight: 465.62
Molecular Formula: C26H43NO6
EC Number: 207-494-9

FabriChem Specifications

ITEMSSPECIFICATIONS
DescriptionWhite or nearly white crystalline powder
Identification (IR)Positive
Clarity of Solution
(C=9% w/v in water neutr. NaOH)
Not more opalescent than Ref. Sol. I (Eur.Ph.curr.ed)
Color of Solution
(C=9% w/v in water neutr. NaOH)
Not more than Ref. Sol. I (Eur.Ph.curr.ed)
Color of Solution
(C=10% w/v in methanol)
Not more than Y6 or BY6
(Eur.Ph.curr.ed)
pH3.0 – 4.0
Water Content (KF)5.0% Max.
Specific Rotation (on dried basis)
(C = 1% Methanol)
+31.5° ± 2°
Assay (on dried basis)98.0 – 101.0%
Residue on Ignition0.2% Max.
Heavy Metals20 ppm Max.
Iron10 ppm Max.
Chloride100 ppm Max.
Residual Solvent (Ethanol)500 ppm Max.
Residual Solvent (Ethyl Acetate)100 ppm Max.
Chromatographic Assays (TLC):
Cholic Acid0.5% Max.
Glycodeoxycholic Acid1.0% Max.
Glycine0.2% Max.
Other unidentified related substances (each)0.2% Max.
Other unidentified related substances (total)0.5% Max.

Total sum of all impurities3.0% Max.

Molecular Structure
glycocholic-acid-structure

About

Glycocholic Acid is crystalline bile acid involved in the emulsification of fats. As the Glycine conjugate of Cholic Acid, this compound acts as a detergent to solubilize fats for absorption and is itself absorbed.

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