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D-Glucuronolactone

Synonyms


D-(+)-Glucurono-6,3-lactone, D-Glucurono-6,3-lactone,
D-Glucurone, Glucuronolactone

Technical Data

CAS Number: 32449-92-6
Molecular Formula: C6H8O6
Molecular Weight: 176.12
Beilstein Registry Number: 83595
EC Number: 251-053-3

FabriChem Specifications

ITEMSSPECIFICATIONS
DescriptionWhite crystals or crystalline powder
IdentificationPositive
Melting Point170°C - 176°C
Sulfate0.010% Max.
Chloride0011% Max.
Heavy Metals (as Pb)10 ppm Max.
Arsenic2 ppm Max.
Loss on Drying0.2% Max.
Residue on Ignition0.1% Max.
Clarity & Color of SolutionClear and Colorless
Specific Rotation+18.0° to +20.0°
Assay98.5 – 102.0%
Microbiology:
Total Plate Count3,000 CFU/g Max.
Yeast & Mold300 CFU/g Max.
E. ColiNot Detected
SalmonellaNot Detected

Molecular Structure
d-glucuronolactone-structure

About

Glucuronolactone is metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis.

The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. Glucuronides combine with toxic substances, such as morphine and depot medroxyprogesterone acetate, by converting them to water-soluble glucuronide-conjugates which are then excreted from the body. Glucuronolactone is a popular ingredient in applications for detoxification.

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