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Chlorpheniramine Maleate USP

Synonyms


(±)-Chlorpheniramine maleate salt; 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine

Technical Data

CAS Number: 113-92-8
Molecular Formula: C16H19ClN2 · C4H4O4
Molecular Weight: 390.86
EC Number: 204-037-5

FabriChem Specifications

ITEMSSPECIFICATIONS
DescriptionWhite, odorless, crystalline powder
SolubilityFreely soluble in water, soluble in alcohol and in chloroform, slightly soluble in ether and in benzene
Identification (IR)The infrared absorption spectrum should be concordant with the reference spectrum of chlorpheniramine maleate
Melting Range130˚ - 135˚ C
Loss on Drying0.5% Max.
Residue on Ignition0.2% Max.
Related CompoundsTotal impurity
NMT 2.0%
Assay (on dried basis)98.0 – 100.5%
Residual Solvents:
Isopropanol5,000 ppm Max.
O-Xylene2,170 ppm Max.
Methanol3,000 ppm Max.

Molecular Structure

chlorpheniramine-maleate-usp-structure

About

Chlorpheniramine Maleate is a halogenated amine. Amines are chemical bases, and they neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.

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