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Dehydroepiandrosterone

Synonyms

trans-Dehydroandrosterone, 3β-Hydroxy-5-androsten-17-one, 5-Androsten-3β-ol-17-one,
DHEA, Dehydroepiandrosterone, Dehydroisoandrosterone, Prasterone

Technical Data

CAS Number: 53-43-0
Molecular Formula: C19H28O2
Molecular Weight: 288.42
EC Number: 200-175-5

FabriChem Specifications

ITEMSSPECIFICATIONS
AppearanceWhite or almost white
crystalline powder
Assay (HPLC)98.5% - 102.0%
Melting Point149° – 151°C
Specific Rotation+12° to +15°
Loss on Drying0.5% Max.
Sulfated Ash0.1% Max.
Related Substances:Any Impurity: 0.10% Max.
Total Impurities: 0.50% Max.
Total Heavy Metals10 ppm Max.
Lead 3 ppm Max.
Arsenic (As)1 ppm Max.
Mercury0.1 ppm Max.
Cadmium1 ppm Max.
Bulk DensityReport Only
Tapped DensityReport Only
Particle SizeReport Only
Microbiology:
Total Plate Count1,000 CFU/g Max.
Yeast & Mold100 CFU/g Max.
ColiformNegative
E. ColiNegative

Molecular Structure

dehydroandrosterone-structure

About

Dehydroandrosterone (DHEA) is a negative modulator of GABAA receptors. It is a steroid secreted by the adrenal gland with both estrogenic and androgenic properties. DHEAs conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.

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